Antibiotics in the treatment of trophic ulcers of the lower extremities: which are the most effective?

2023 Author: Alfred Shackley | [email protected]. Last modified: 2023-05-21 13:14

Diseases associated with metabolic disorders or blood outflow, as well as burns and skin injuries can provoke the appearance of a trophic ulcer on the legs. In most cases, complications after thrombosis of veins in the legs lead to this pathology.

Antibiotics in the treatment of trophic ulcers are prescribed in order to cleanse the wound from the accumulation of purulent secretions, as well as to accelerate the regeneration process of the affected tissues. If the pathogenic microflora in the patient's body is not found, the doctor will also prescribe antibiotic therapy for prevention. Fortunately, the choice of such medicines is great.

Dioxidine is a time-tested antibiotic

For thirty years, the antibiotic dioxidine has been used in Russian medicine.

This drug has an antimicrobial effect in the treatment of purulent-infectious processes.

Dioxidine is used externally, intravenously and intracavitary. The solution of this antibacterial agent has a yellowish color. The main substance is hydroxymethylquinoxylindoxide.

To use an antibiotic for trophic ulcers, moisten a piece of gauze in a 1% Dioxidine solution and apply to the surface of the wound, previously cleaned of pus.

Change the tampon every day or every other day, depending on the degree of damage and the rate of healing. Deep wounds are treated with 0.5% Dioxidine solution.

This drug should not be used in such cases:

• disruption of the adrenal glands;
• lactation period and pregnancy;
• individual intolerance to the product;
• children and adolescents up to eighteen years old.

As a rule, local treatment of a trophic ulcer with this antibiotic is well tolerated.

Argosulfan: an effective topical treatment

Antibacterial cream Argosulfan, the main component of which is silver sulfathiazole, disinfects a trophic wound, neutralizes harmful microorganisms and heals ulcers in a short time. Silver ions in the preparation inhibit microbial cell division. Due to its hydrophilic base, the cream has an analgesic effect.

The indications for the appointment of this antibacterial agent are the following conditions:

• purulent wounds;
• severe frostbite;
• bedsores;
• thermal and chemical burns;
• abrasions, cuts;
• trophic ulcers of the leg.

Before applying the antibacterial ointment, treat the ulcer and adjacent tissues with a 1% solution of Iodopyrine. Then apply two to three millimeters of Argosulfan cream to the wound. Repeat the procedure three times a day. The maximum allowable daily intake of the drug is twenty-five milligrams. The duration of therapy with Argosulfan should not exceed two months.

The dressing is changed every day or every other day, depending on how wet the dressing is. The silver salt of sulfathiazole maintains a constant concentration of the drug in the tissues of the ulcer.

Argosulfan should not be used to treat trophic wounds on the lower extremities in the following cases:

• treatment of premature babies and babies under two months of age;
• period of breastfeeding;
• hypersensitivity to sulfathiazole.

The use of this antibiotic for trophic ulcers on the legs stops the infectious process in the wound and eliminates pain.

Sintomycin-Rusfar: aerosol for topical use

Synthomycin-Rusfar is a bacteriostatic antibiotic with a wide spectrum of action. The active ingredient chloramphenicol in the composition of the drug heals trophic wounds and accelerates epithelialization.

Sintomycin-Rusfar is prescribed for the following diseases:

• trophic ulcers of the leg;
• boils;
• bacterial skin infections;
• bedsores;
• infected burns.

Remove the cap from the balloon before using the medicine.

Press the spray head and spray the preparation on the sore lower leg from a distance of twenty to thirty centimeters. The procedure is carried out three times a week.

Syntomycin-Rusfar should not be used in such cases:

• hypersensitivity to the active substance;
• psoriasis, fungal infections, eczema;
• extensive granulating wounds;
• pregnancy;
• childhood.

During treatment, it is necessary to systematically monitor the peripheral blood picture.

Heliomycin is an effective ointment for lower limb health

Heliomycin is available in the form of an ointment for external use. The active substance of the drug is heliomycin.

This antibiotic is prescribed for the following diseases:

• trophic ulcer of the leg caused by venous insufficiency;
• infected eczema;
• purulent inflammation of the skin;
• pemphigus of newborns;
• bedsores;
• cracks;
• rhinitis.

Ointment Heliomycin is applied to the affected area of the skin twice a day. Ten minutes after applying the drug, a bandage is applied. The treatment lasts five to seven days. Contraindication to the appointment of Heliomycin is hypersensitivity to the components.

Tetracycline ointment: a quick fix

In the treatment of trophic ulcers, tetracycline ointment is used, which is a bacteriostatic antibiotic. This drug stops the multiplication of pathogenic microorganisms. Tetracycline copes with staphylococcal, gonorrheal, streptococcal, salmonella and other infections.

Tetracycline ointment is prescribed for the following skin diseases:

• acne;
• furunculosis;
• eczema complicated by infection;
• trophic ulcers of the lower extremities;
• folliculitis.

The drug is applied to the affected skin area twice a day.

Tetraceclin ointment should not be used in such cases:

• hypersensitivity to tetracycline;
• lesions of the skin of a mycotic nature;
• children's age up to eleven years;
• lactation period and pregnancy.
• liver failure.

The duration of treatment with Tetracycline ointment is determined individually.

Levomekol: antibiotic and immunostimulant in one tube

The components of Levomekol ointment have antibacterial, anti-inflammatory and regenerating effects. Levomekol contains chloramphenicol and methyluracil. Chloramphenicol has an antimicrobial effect. Methyluracil heals wounds and regenerates tissue. Also, this substance is an immunostimulant that has an antiviral effect.

Levomekol is prescribed for the following conditions:

• trophic ulcers;
• purulent-inflammatory skin diseases;
• purulent wounds;
• second and third degree burns;
• boils.

For the treatment of a trophic ulcer of the lower extremity, an antibiotic is applied in a thin layer to the lesion site and the treated area is covered with sterile gauze.

The wound is cleaned twice a day. Levomekol should not be taken in case of hypersensitivity to the components.

Before using antibiotics for trophic ulcers of the lower extremities, conduct a bacteriological study. Such potent medicines are prescribed only by a doctor. Thoughtlessly taking antibacterial drugs will make recovery more difficult.